What is REGRANEX Gel?

How is REGRANEX Gel different from other wound care therapies?

Is REGRANEX Gel right for me?

Is REGRANEX Gel safe, and are there any side effects?

Can I use REGRANEX Gel if I am using other medications on the wound?

Is REGRANEX Gel covered by my insurance plan?

What does "good wound care" mean?

Why does my doctor cut open my wound just when it seems to be healing?

What can I do to help my wound heal?

Can REGRANEX Gel be kept in my medicine cabinet?

How should I apply REGRANEX Gel to my wound?

How long do I have to use REGRANEX Gel?

What if I forget to apply REGRANEX Gel?

How long will it be before I notice my wound healing?

What is REGRANEX Gel?

REGRANEX Gel is the only FDA-approved prescription medicine that contains platelet-derived growth factor (PDGF), a powerful, natural substance that helps your body heal. It is applied directly to the foot ulcer. REGRANEX Gel, in conjunction with good wound care, has been proven to help heal diabetic foot ulcers more effectively than standard wound care.

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How is REGRANEX Gel different from other wound care therapies?

You may have heard of, or even tried, other treatments for diabetic foot ulcers. Most of these treatments help keep the wound clean and moist. REGRANEX Gel is different because it is the only FDA-approved prescription medicine that contains a growth factor that helps your body heal.

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Is REGRANEX Gel right for me?

Some wounds take a long time to heal. REGRANEX Gel can help this problem in many patients by delivering growth factor directly to the foot ulcer.

If you have diabetes, you may need to take insulin because your body does not make enough insulin or because your cells do not use it well. In a similar way, you may need REGRANEX Gel because your body may not make enough of the growth factor you need for your wound to properly close and heal. REGRANEX Gel gives you more growth factor than the amount you have, so your diabetic foot wound can heal more normally.

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Is REGRANEX Gel safe, and are there any side effects?

REGRANEX Gel has been tested and found to be safe on hundreds of patients. When used correctly, REGRANEX Gel is generally well tolerated. REGRANEX Gel should not be used in patients with cancers at the site of application. In a safety study, patients treated with 3 or more tubes of REGRANEX Gel had an increased risk of death from cancer at locations in the body other than the ulcer. Talk to your doctor about risks of cancer and tell your doctor if you have or have had cancer.



In clinical studies, a small percentage of patients treated with REGRANEX Gel or placebo gel experienced rash near the wound. REGRANEX Gel should not be used by patients sensitive to any components of this product.

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Can I use REGRANEX Gel if I am using other medications on the wound?

If you have been using products such as creams, gels, or ointments on the wound, you should let your doctor or healthcare professional know. REGRANEX Gel has not been studied alongside these types of products.

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Is REGRANEX Gel covered by my insurance plan?

REGRANEX Gel is covered by most prescription plans and by Medicaid. Please ask your doctor or insurance provider to see if REGRANEX Gel is covered. SYSTAGENIX Wound Management, the marketer of REGRANEX Gel, can also help your doctor find out if REGRANEX Gel is covered.

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What does "good wound care" mean?

For REGRANEX Gel to be effective, good wound care must be followed. Good wound care includes:

• Your doctor or healthcare professional removing dead skin/debris from the wound whenever necessary
• Keeping weight off your feet, perhaps by wearing special orthopedic shoes or by other methods
• Your doctor or healthcare professional treating any infection of the wound
• Continuing to visit your doctor or healthcare professional and following your treatment plan

Why does my doctor cut open my wound just when it seems to be healing?

Most diabetic foot ulcers will need to have dead tissue removed before healing can happen. There are many methods for removing dead tissue. Sharp debridement is a common procedure in which your doctor uses a sharp instrument to remove the dead tissue from your diabetic foot ulcer. Sharp debridement is an accepted and proven way to get rid of dead tissue from a wound and to draw healthy blood to the diabetic foot ulcer. It is necessary for starting the healing process. If necessary, your doctor can give you a numbing medicine (anesthetic) so that you will feel no pain. After sharp debridement, your diabetic foot ulcer may look bigger or even bleed. Don't be alarmed. The diabetic foot ulcer may look bigger, but it will be healthier because your doctor has cut away the dead tissue. You should have your ulcer debrided every 7 to 10 days until the wound is free of dead tissue. Your diabetic foot ulcer now has a better chance to heal.

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What can I do to help my wound heal?

The best thing you can do for yourself is to follow your doctor's or healthcare professional's instructions, as well as the guidelines listed above. Following this healthy regimen will increase your chances of healing your wound completely.

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Can REGRANEX Gel be kept in my medicine cabinet?

No. REGRANEX Gel must be kept in your refrigerator (never in your freezer).

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How should I apply REGRANEX Gel to my wound?

Apply a thin continuous layer of REGRANEX Gel (enough to cover the surface of the wound) as instructed by your doctor or healthcare professional once a day, and then cover with a fresh, moist dressing. DO NOT apply REGRANEX Gel a second time in one day. Click here to learn how to apply REGRANEX Gel.

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How long do I have to use REGRANEX Gel?

Most people continue to use REGRANEX Gel until their wound has completely healed; however, healing times are different for everyone, and they often depend on the severity of the wound. Sometimes a wound can look healed when it's really not. Therefore, you should continue to use REGRANEX Gel until your doctor or healthcare professional tells you to stop.

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What if I forget to apply REGRANEX Gel?

If you forget to apply REGRANEX Gel, simply continue on your regular schedule of therapy. DO NOT apply 2 doses of REGRANEX Gel to make up for missing a dose.

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How long will it be before I notice my wound healing?

Healing times are different for everyone, but the important thing is not to get discouraged. Although it may take weeks or even months to completely heal your wound, you know that by practicing good wound care and applying REGRANEX Gel correctly, you are doing everything you can to help the healing process. Follow the helpful hints to help prevent these wounds in the future.

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Click here for free diabetic foot wound information